Unveiling Physics in Biology by Optical Manipulation of Single Molecules

In the Optical Nanomanipulation Laboratory, at IMDEA-Nanoscience, we work in the field of Molecular and Cell Biophysics, furthering the study of the macromolecules that make up the machinery of cells. Our laboratory attempts to increase the understanding of the molecules of life beyond the biochemical viewpoint. Biological molecules have traditionally been studied with bulk biochemical methods, where a large number of these are analyzed simultaneously. These macroscopic experiments provide ensemble and time averages of the individual characteristics of each molecule. The set of deterministic properties and slow variation thus obtained result in an idealized image, that is, molecules with slow and well defined dynamics. Yet at the level of individual molecules, the picture is very different: one can find them in states that are far from the average behavior of the population, and their instantaneous dynamics are rapid and highly random. 

Seminar presented by R. Arias-González from the Instituto Madrileño de Estudios Avanzados en Nanociencia. For the full announcement download the presentation notice.