Foto de 2010








Alveolar Cells and Lung Surfactant


Director: Prof. Cristina Casals


Our laboratory has studied the pulmonary surfactant system under normal and pathological conditions for more than 20 years. The main lines of research are:

  • Membrane biochemistry and biophysics.

  • Structure-function relationships in surfactant proteins.

  • Role of pulmonary surfactant in lung physiopathology.

These studies employ an array of techniques including biophysical, biochemical, immunological, cellular, and physiological.



Key words:


Membranes, monolayers, SP-A, SP-B, SP-C, collectins, lipid-protein interaction, protein-protein interaction, collagen, bacterial lipopolysaccharide, beta-(1,3) glucan, FK506, KL4, alveolar macrophages, type II cells, innate immune defence, acute lung injury, and lung transplantation.



Public Funding:


MICINN National Program of Research and Development

Ciberes Spanish Research Center of Respiratory Diseases

CAMAutonomous Community of Madrid-Innovation and Research System



Private Funding:


Nycomed GmbH, Germany

Fujisawa GmbH, Gernany

Laboratorios Dr. Esteve, Barcelona

Fundación MM, Madrid





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