Medicinal Chemistry Lab
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Publications
Use menu on the left to navigate through Lab publications, sorted by year. Follow the link to access each one of them.

Publications 2020 - Current


Competitive upconversion-linked immunoassay using peptide mimetics for the detection of the mycotoxin zearalenone

Authors: R. Peltomaa, Z. Farka, M.J. Mickert, J.C. Brandmeier, M. Pastucha, A. Hlavá?ek, M. Martínez-Orts, Á. Canales, P. Skládal, E. Benito-Peña, M.C. Moreno-Bondi, H.H. Gorris
Publication: Biosens. Bioelectron.
Year: 2020 Volume: 170 Pages: 112683 to 112691
[Check out this article at Pubmed] PublMed


Efficient chemoenzymatic synthesis of N-glycans with a beta-1,4-galactosylated bisecting GlcNAc motif

Authors: M. Weiss, D. Ott, T. Karagiannis, M. Weishaupt, M. Niemietz, S. Eller, M. Lott, M. Martínez-Orts, Á. Canales, N. Razi, J.C. Paulson, C. Unverzagt
Publication: ChemBioChem
Year: 2020 Volume: 21 Pages: 3212 to 3215
[Check out this article at Pubmed] PublMed


Glucose metabolism links astroglial mitochondria to cannabinoid effects

Authors: D. Jimenez-Blasco, A. Busquets-Garcia, E. Hebert-Chatelain, R. Serrat, C. Vicente-Gutierrez, C. Ioannidou, P. Gómez-Sotres, I. Lopez-Fabuel, M. Resch-Beusher, E. Resel, D. Arnouil, D. Saraswat, M. Varilh, A. Cannich, F. Julio-Kalajzic, I. Bonilla-Del Río, A. Almeida, N. Puente, S. Achicallende, M.L. López-Rodríguez, C. Jollé, N. Déglon, L. Pellerin, C. Josephine, G. Bonvento, A. Panatier, B. Lutz, P.-V. Piazza, M. Guzmán, L. Bellocchio, A.-K. Bouzier-Sore, P. Grandes, J.P. Bolaños, G. Marsicano
Publication: Nature
Year: 2020 Volume: 583 Pages: 603 to 608
[Check out this article at Pubmed] PublMed


A novel agonist of the type 1 lysophosphatidic acid receptor (LPA1), UCM-05194, shows efficacy in neuropathic pain amelioration

Authors: I. Gonzalez-Gil, D. Zian, H. Vázquez-Villa, G. Hernandez-Torres, R.F. Martinez, N. Khiar-Fernandez, R. Rivera, Y. Kihara, I. Devesa, S. Mathivanan, C. Rosell del Valle, E. Zambrana-Infantes, M. Puigdomenech, G. Cincilla, M. Sanchez-Martinez, F. Rodriguez de Fonseca, A. Ferrer-Montiel, J. Chun, R. Lopez-Vales, M.L. López-Rodríguez, S. Ortega-Gutierrez
Publication: J. Med. Chem.
Year: 2020 Volume: 63 Pages: 2372 to 2390
[Check out this article at Pubmed] PublMed


Serum endocannabinoid levels in suicide attempters: A pilot study

Authors: J. Herranz-Herrer, E. Gil-Benito, T. Ponte-López, S. Ortega-Gutiérrez, J. Macicior, S. Rosado-Garcia, A.J. Sánchez-López, H. Blasco-Fontecilla
Publication: Eur. Neuropsychopharmacol.
Year: 2020 Volume: 40 Pages: 52 to 60
[Check out this article at Pubmed] PublMed


Membrane disruption, but not metabolic rewiring, is the key mechanism of anticancer action of FASN inhibitors: a multi-omics analysis in ovarian cancer

Authors: T.W. Grunt, A. Slany, M. Semkova, R. Colomer, M.L. López-Rodríguez, M. Wuczkowski, R. Wagner, C. Gerner, G. Stübiger
Publication: Sci. Rep.
Year: 2020 Volume: 10 Pages: 14877 to 14887
[Check out this article at Pubmed] PublMed


The cannabinoid WIN55212-2 restores rhinovirus-induced epithelial barrier disruption

Authors: A. Angelina, M. Martín-Fontecha, B. Rückert, P. Wawrzyniak, M. Pérez-Diego, J. López-Abente, M. Akdis, C.A. Akdis, O. Palomares
Publication: Allergy
Year: 2021 Volume: 76 Pages: 1900 to 1902
[Check out this article at Pubmed] PublMed


Chemistry for the identification of therapeutic targets: Recent advances and future directions

Authors: N. Khiar-Fernandez, J. Macicior, B. Marcos-Ramiro, S. Ortega-Gutierrez
Publication: Eur. J. Org. Chem.
Year: 2021 Volume: 2021 Pages: 1307 to 1320
[Check out this article at Pubmed] PublMed


The pharmacological or genetic blockade of endogenous de novo fatty acid synthesis does not increase the uptake of exogenous lipids in ovarian cancer cells

Authors: T.W. Grunt, L. Lemberger, R. Colomer, M.L. López-Rodríguez, R. Wagner
Publication: Front. Oncol. doi: 10.3389/fonc.2021.610885
Year: 2021 Volume: 11 Pages: 610885 to 610895
[Check out this article at Pubmed] PublMed


Targeting the FtsZ allosteric binding site with a novel fluorescence polarization screen, cytological and structural approaches for antibacterial discovery

Authors: S. Huecas, L. Araújo-Bazán, F.M. Ruiz, L.B. Ruiz-Ávila, R.F. Martínez, A. Escobar-Peña, M. Artola, H. Vázquez-Villa, M. Martín-Fontecha, C. Fernández-Tornero, M.L. López-Rodríguez, J.M. Andreu
Publication: J. Med. Chem.
Year: 2021 Volume: 64 Pages: 5730 to 5745
[Check out this article at Pubmed] PublMed


Small-molecule therapeutic perspectives for the treatment of progeria

Authors: J. Macicior, B. Marcos-Ramiro, S. Ortega-Gutiérrez
Publication: Int. J. Mol. Sci. doi: 10.3390/ijms22137190
Year: 2021 Volume: 22 Pages: 0 to 0
[Check out this article at Pubmed] PublMed


Isoprenylcysteine carboxylmethyltransferase-based therapy for Hutchinson–Gilford progeria syndrome

Authors: B. Marcos-Ramiro, A. Gil-Ordóñez, N.I. Marín-Ramos, F. J. Ortega-Nogales, M. Balabasquer, P. Gonzalo, N. Khiar-Fernández, L. Rolas, A. Barkaway, S. Nourshargh, V. Andrés, M. Martín-Fontecha, M.L. López-Rodríguez, S. Ortega-Gutiérrez
Publication: ACS Cent. Sci. doi: 10.1021/acscentsci.0c01698
Year: 2021 Volume: 0 Pages: 0 to 0
[Check out this article at Pubmed] PublMed



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